| Splenic
leukemia is more common with chronic forms of the disease, denoting a
poorer prognosis. These individuals tend to display marked splenomegaly
on CT (greater than 400 grams) but maintaining a homogeneous enhancement
pattern. This marked enlargement leaves these patients prone to splenic
rupture and infarction. These complications are potentially life threatening,
occurring in 0.72% of adults and 0.18% of children. Rarely, leukemia may
also involve the spleen producing focal nodular lesions.
|